Step 2 review: Pharm

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Author:
jennmlee
ID:
95567
Filename:
Step 2 review: Pharm
Updated:
2011-07-29 22:51:11
Tags:
Step2 pharm drug side effects
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Description:
Step 2 review items from First Aid
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  1. HMG-CoA reductase: effect on lipids, side effects
    • dec LDL, dec trigs
    • inc LFTs
    • myositis
    • warfarin potentiation
  2. Lipoprotein lipase stimulators: effect on lipids, side effects
    • dec trigs, inc HDL
    • GI upset
    • cholelithiasis
    • myositis
    • inc LFTs
  3. Ezetimibe: effect on lipids, side effects
    • dec LDL
    • diarrhea
    • abdominal pain
    • watch out for angioedema
  4. Niacin: effect on lipids, side effects
    • inc HDL, dec LDL
    • skin flushing
    • paresthesias
    • pruritus
    • GI upset
    • inc LFTs
  5. Cholestyramine, colestipol: effect on lipids, side effects
    • dec LDL
    • constipation, GI upset
    • LFT abnormalities
    • myalgias
    • dec absoprtion of other drugs
  6. Antihypertensive for diabetics c proteinuria
    ACEi or ARB
  7. Antihypertensive for CHF pts
    • beta blockers
    • ACEi or ARB
    • diuretics
  8. Antihypertensive for MI pts
    • beta blockers without intrinsic sympathomimetic activity
    • ACEi
  9. Antihypertensive for pts c osteoporosis
    thiazide
  10. beta blockers: side effects
    • hypokalemia: muscle weakness, arrythmia, EKG changes
    • headache
    • tremor
    • palpitation
  11. drug fever: usual culprits
    • occurs 1-2 wks after exposure
    • anticonvulsants
    • TMP-SMX
  12. Trastuzumab: what does it do, side effects
    • monoclonal antibody used to treat HER2+ breast cancer
    • cardiotoxicity- perform echo before giving

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