Random Drug Questions

combo may increase simvastatin level, risk of myopahty, rhabdomyolysis

CYP2C8

None

• 5 refills
• Refills are valid for up to 6 months from written date.

• National Precursor Log Exchange
• Dear valued customer, as you may be aware, many cold and allergy medications containing pseudoephedrine are regulated by state & federal laws. Sales of these medications are monitored to help stop the illicit manufacture of methamphetamine and other dangerous drugs.

Promethazine (Phenergan) is a 1st generation antihistamine that is used for the prevention of n/v. However, taking this medication can cause drowsiness.

BBW: cannot give promethazine to children < 2 y/o d/t fatal respiratory depression.

• S = salivation stimulation
• L = lacrimation stimulation
• U = urination (relaxation of the internal sphincter muscle of urethra)
• D = defecation (relaxation of internal anal sphincter)
• G = gastrointestinal upset (diarrea)
• E = emesis (vomiting)
• M = miosis/muscle spasm (pupillary constrictor)

• nervousness
• irritability
• difficulty sleeping
• unblinking stare
• hoarseness/deep voice
• dry/sore throat
• difficulty swallowing
• rapid heartbeat
• menstrual irregularities
• infertility
• weight loss
• frequent bowel movements
• increased sweating
• warm, moist palms
• excessive vomiting in pregnancy

• tiredness
• puffy eyes
• forgetfullness/slower thinking
• moodiness/irritability
• hoarseness/deepening of voice
• depression
• dry/sore throat
• difficult swallowing
• thinning hair/hair loss
• slower heartbeat
• loss of body hair
• menstrual irregularities
• infertility
• constipation
• dry skin
• weight gain
• cold intolerance
• muscle weakness/cramps
• elevated cholesterol

n/v can cause a lot of patients to throw-up & loosing water. Therefore, dehydration is a common thing. Ask parents to replenish with popsicle or any other water source and refer them to see a PCP.

No b/c montelukast (Singulair) is a leukotriene inhibitor that can only prevent asthma from happening, NOT treating it.

methotrexate (Trexall) is a DMARDs & immunosuppressnat drug that requires the administration of folic acid to reduce hematologic, gastrointestinal, & hepatic adverse events

coughing d/t bradykinin release

tardive dyskinesia - involuntary muscle movement

chlorpheniramine/hydrocodone

5 mL every 12 hours; do not exceed 10 mL/24 hours

chlordiazepoxide/clidinium

Concurrent use of CLIDINIUM and POTASSIUM CHLORIDE may result in risk of gastrointestinal lesions.

• sertraline
• Antidepressant
• SSRIs
• selectively inhibits serotonin reuptake

• citalopram
• Antidepressant
• SSRIs
• selectively inhibits serotonin reuptake

• paroxetine
• Antidepressant
• SSRIs
• selectively inhibits serotonin reuptake

• venlafaxine (Effexor)
• duloxetine (Cymbalta)
• milnacipran (Savella)

• trazodone
• Antidepressant
• SARI
• inhibits serotonin reuptake, antagonizes alpha-1 adrenergic and serotonin 5-HT2A/C receptors

delays absorption by allowing the drug to reach the stomach before it is breaking down for absorption

• 1st-Gen = sedation
• cetirizine (Zyrtec)
• chlorpheniramine (Chlor-Trimeton)
• diphenhydramine (Benadryl)
• promethazine (Phenergan)

• 2nd-Gen = non-sedation
• cimetidine (Tagamet)
• famotidine (Pepcid)
• ranitidine (Zantac)