Top 200 (Brand/Generic)

Card Set Information

Author:
skylinezts
ID:
95976
Filename:
Top 200 (Brand/Generic)
Updated:
2011-08-20 14:26:38
Tags:
Top Brand Generic
Folders:

Description:
Top 200 (Brand/Generic)
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user skylinezts on FreezingBlue Flashcards. What would you like to do?


  1. Abilify
    • aripiprazole
    • Atypical antipsychotic
    • Bipolar Disorder
    • agonizes D2 & 5-HT1A receptors, antagonizes 5-HT2A receptors
    • BBW: Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: extrapyramidal disease, somnolence, anxiety, weight gain, akathisia, HA
  2. Accupril
    • quinapril
    • Antihypertensive/HF
    • ACE Inhibitor
    • inhibits angiotensin converting enzyme, interfering w/ conversion of angiotensin I to angiotensin II
    • BBW: fetal death
    • SE: dizziness, HA, cough, hypotension, fatigue, hyperkalemia,BUN/SCr increased
  3. Aciphex
    • rabeprazole
    • Gastric antisecretory; PPIs
    • inhibits gastric parietal cell hydrogen-potassium ATPase (proton pump inhibitor)
    • SE: abdominal pain, HA, diarrhea, N/V
  4. Actonel
    • risedronate
    • Osteoporosis agent
    • Biphosphonate
    • inhibits osteoclast activity, reducing bone resorption and turnover (bisphosphonate)
  5. Actos
    • pioglitazone
    • Antidiabetic
    • thiazolidinediones
    • increases insulin sensitivity
    • SE: edema, upper respiratory infection, sinusitis, pharyngitis
    • BBW: HF
  6. Advair HFA
    • fluticasone + salmeterol inhaled
    • Antiasthmatic
    • Corticosteroid/Beta-2 agonist (long-acting)
    • BBW: Long-acting beta 2-adrenergic agonists (LABA), such as salmeterol, one of the active ingredients in the fluticasone propionate/salmeterol inhalation powder and aerosol , increase the risk of asthma-related death
  7. Aldactone
    • spirinolactone
    • Antihypertensive
    • K+ sparing diuretics
    • antagonizes distal convoluted tubule aldosterone receptors
    • BBW: tumorigen
    • SE: gynecomastia, HA, diarrhea
  8. Allegra-D
    • fexofenadine + pseudoephedrine
    • Antihistamine/decongestant
  9. Altace
    • ramipril
    • ACE Inhibitor
    • antihypertensive
    • inhibits angiotensin converting enzyme, interfering w/ conversion of angiotensin I to angiotensin II
    • SE: cough, hypotension, headache, dizziness
    • BBW: fetal death
  10. Amaryl
    • glimepiride
    • Antidiabetic
    • Sulfonylureas
    • stimulates pancreatic islet beta cell insulin release
    • SE: hypoglycemia, dizziness, HA
  11. Ambien
    • zolpidem
    • Restrictions: C-IV
    • Hypnotic sedative
    • Insomnia
    • interacts w/ GABA; agonism at BZD-1 receptor
    • SE: dizziness, somnolence, headache
  12. Amoxil
    • amoxicillin
    • Penicillin antibiotic
    • SE: diarrhea
  13. Flexeril
    • cyclobenzaprine
    • Muscle relaxant
    • centrally-acting muscle relaxant
    • SE: xerostomia, drowsiness, dizziness
  14. Anaprox
    • naproxen
    • NSAIDs
    • inhibits cyclooxygenase, reducing prostaglandin and thromboxane synthesis
  15. Antivert
    • meclizine
    • Anti-vertigo
    • Antihistamine, 1st generation
    • antagonizes central and peripheral H1 receptors (non-selective antihistamine); antagonizes cholinergic receptors, producing antiemetic effects
    • SE: sedated, xerostomia, somnolence
  16. Aricept
    • donepezil
    • Antipsychotic/Alzheimer's Disease/Dementia
    • cholinesterase inhibitor
    • reversibly binds to and inactivates acetylcholinesterase
    • SE: insomnia, diarrhea, N/V, cramp
  17. Armour Thyroid
    • thyroid (porcine)
    • Hypothyroidism
    • thyroid hormone
    • natural T3 and T4 mixture: produces various physiologic effects, including increasing metabolism
    • SE: tremor, restlessness, palpitation, sweating,tachycardia, insomnia
    • BBW: not for obesity treatment
  18. Astelin
    • azelastine nasal
    • Antiallergy
    • Antihistamine, 1st Gen
    • antagonizes central and peripheral H1 receptors
  19. Vistaril
    • hydroxyzine
    • Antianxiety/Antipruritic
    • Antihistamines, 1st generation
    • antagonizes central and peripheral H1 receptors
    • SE: xerostomia, HA, somnolence
  20. Ativan
    • lorezapam
    • Antianxiety
    • BZDs 2: Mid-acting
    • binds to benzodiazepine receptors; enhances GABA effects
    • SE: dizziness, sedated, asthenia
  21. Augmentin
    • amoxicillin/clavulanate
    • PCN/penicillinase inhibitor
    • bactericidal; inhibits cell wall mucopeptide synthesis / inhibits beta-lactamases
    • SE: diarrhea
  22. Avalide
    • irbesartan/hydrochlorothiazide
    • ARB/Thiazide combos
    • Antihypertensive
    • BBW: fetal death
    • SE: muscular pain, dizziness, HA, fatigue
  23. Avandia
    • rosiglitazone
    • Antidiabetic
    • Thiazolidinediones
    • increases insulin sensitivity
    • BBW: heart failure
    • SE: edema, weight gain
  24. Avapro
    • irbesartan
    • ARBs
    • Antihypertensive
    • selectively antagonizes angiotensin II AT1 receptors
    • BBW: fetal death
    • SE: HA, fatigue
  25. Avelox
    • moxifloxacin
    • Fluoroquinolones antibiotic
    • bactericidal; inhibits DNA gyrase and topoisomerase IV
    • BBW: tendonitis
    • SE: diarrhea, dry eyes
  26. Avodart
    • dutasteride
    • BPH
    • prostate anti-inflammatory
    • inhibits types I and II 5-alpha-reductase, interfering w/ conversion of testosterone to 5-alpha-dihydrotestosterone
    • SE: reduced libidio, ejaculation disorder, impotence, disorder of breast
  27. Bactrim
    • sulfamethoxazole/trimethoprim
    • Sulfonamide antibiotics
    • for sulfamethoxazole: bacteriostatic; competitively inhibits bacterial or fungal dihydropteroate synthetase, preventing PABA conversion to folic acid and inhibiting growth
    • SE: Stevens-Johnson syndrome, C. diff diarrhea
  28. Bactroban
    • mupirocin topical
    • Antibacterial - (Nasal - MRSA) (Topical - impetigo, S. aureus/S. pyogenes lesions)
    • selectively binds to bacterial isoleucyl transfer-RNA synthetase, inhibiting protein synthesis
    • SE: pruritis, burning sensation
  29. Benicar-HCT
    • olmesartan + HCT
    • ARB/Thiazide combos
    • Antihypertensive
    • BBW: fetal death
    • SE: dizziness, hyperuricemia
  30. Benicar
    • olmesartan
    • ARBs
    • antihypertensive
    • selectively antagonizes angiotensin II AT1 receptors
    • SE: headache, dizziness, hypotension
    • BBW: fetal death
  31. Bentyl
    • dicyclomide
    • GI antispasmotic
    • irritable bowel
    • antagonizes acetylcholine at muscarinic receptors (anticholinergic); relaxes smooth muscle, inhibits bradykinin- and histamine-induced spasms
    • SE: constipation, blurred vision
  32. Biaxin
    • clarithromycin
    • H. pylori
    • Macrolides anitbiotic
    • binds to P site of 50S ribosomal subunit, interfering w/ protein synthesis
    • SE: diarrhea, taste disorder, HA
  33. Boniva
    • ibandronate
    • Osteoporosis agent
    • bisphosphonates
    • inhibits osteoclast activity, reducing bone resorption and turnover
    • SE: upper resp infection, hypertension, indigestion, N/V
  34. BuSpar
    • buspirone
    • Antianxiety agent
    • non-BZD
    • binds to serotonin and dopamine D2 receptors
    • SE: dizziness, nervousness, headache, nausea
  35. Cardizem
    • diltiazem
    • Antiarrhythmias
    • Non-dihydropyridine CCB
    • inhibits calcium ion influx into vascular smooth muscle and myocardium, relaxing smooth muscle, decreasing peripheral vascular resistance, dilating coronary arteries and prolonging AV node refractory period
    • SE: peripheral edema, dizziness, HA, fatigue, bradycardia, cough
  36. Cardura
    • doxazosin
    • BPH agent/Antihypertensive
    • alpha-1 antagonist
    • antagonizes peripheral alpha-1 adrenergic receptors
    • SE: dizziness, fatigue, hypotension, headache
  37. Catapres
    • clonidine
    • Antihypertensive
    • Central alpha-2 agonist
    • stimulates alpha-2 adrenergic receptors
    • SE: AV block
  38. Ceftin
    • cefuroxime
    • 2nd gen, Cephalosporin
    • bactericidal; inhibits cell wall mucopeptide synthesis
    • SE: diarrhea, N/V, vaginitis
  39. Celebrex
    • celecoxib
    • NSAIDs
    • COX-2 inhibitor
    • selectively inhibits cyclooxygenase-2 and reduces prostaglandin synthesis
    • BBW: increase CV thrombotic, MI, stroke, GI bleed
    • SE: hypertension, GI bleed, HA
  40. Celexa
    • citalopram
    • Antidepressants
    • SSRIs
    • selectively inhibits serotonin reuptake
    • BBW: Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: somnolence, tremor, N/V, fatigue, agitation
  41. Chantix
    • varenicline
    • Smoking Cessation Aid
    • Nicotine
    • agonizes and blocks alpha-4-beta-2 nicotinic acetylcholine receptors
    • BBW: Serious neuropsychiatric events (eg, depression, suicidal ideation, suicide attempt and completed suicide) have been reported in patients taking varenicline
    • SE: dream disorder, HA, N/V
  42. Cialis
    • tadalafil
    • Erectile dysfunction
    • inhibits phosphodiesterase type 5, enhancing effects of nitric oxide-activated increases in cGMP
    • SE: HA, flushing, nasopharyngitis, myalgia
  43. Cipro
    • ciprofloxacin
    • Fluorosuinolon antibiotic
    • bactericidal; inhibits DNA gyrase and topoisomerase IV
    • BBW: tendonitis
    • SE: diarrhea, N/V, burning sensation in eye, eye pain
  44. Cleocin
    • clindamycin
    • Other antibiotics
    • binds to 50S ribosomal subunit, interfering w/ protein synthesis
    • BBW: Pseudomembranous colitis
    • SE: diarrhea, abdominal pain
  45. Cogentin
    • benztropine
    • Anti-Parkinson
    • antagonizes acetylcholine and histamine receptors
    • SE: tachycardia, blurred vision, constipation, nausea
  46. Colcrys
    • colchicine
    • Gout
    • in FMF, interferes w/ inflammasone complex assembly in neutrophils and monocytes, preventing IL-1 activation; in gout, concentrates in PMN cells and inhibits microtubule polymerization, preventing neutrophil migration and activity related to gout sx
    • SE: diarrhea, N/V, myelosuppresion
  47. Combivent
    • ipratropium + albuterol MDI
    • Anti-asthmatic
    • Beta-2 Agonists/Short-acting inhaled
    • SE: upper resp depression, bronchitis, dyspnea
  48. Pacerone
    • amiodarone
    • Anti-arrhythmic
    • class-III
    • prolongs action potential phase 3 (class III antiarrhythmic)
    • SE: photodermatitis, hypotension, bradyarrhythmic
    • BBW: pulmonary toxicity, hepatotoxicity, proarrhythmic effects
  49. Coreg
    • carvedilol
    • Antihypertensive
    • non-selective Beta-blocker
    • selectively antagonizes alpha-1 adrenergic receptors; antagonizes beta-1 and beta-2 adrenergic receptors (selective alpha and non-selective beta blocker)
    • SE: hypotension, bradyarrhythmia, dizziness, fatigue, hyperglycemia
  50. Coumadin
    • warfarin
    • Anticoagulant
    • inhibits vitamin K-dependent coagulation factor synthesis (II, VII, IX, X, proteins C and S)
    • BBW: fatal bleeding
    • SE: bleeding, tissue necrosis, gangrene
  51. Cozaar
    • losartan
    • Antihypertensive
    • ARBs
    • selectively antagonizes angiotensin II AT1 receptors
    • SE: dizziness, fatigue, hypotension
    • BBW: fetal death
  52. Crestor
    • rosuvastatin
    • Antihyperlipidemia
    • Statin
    • inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase
    • SE: myalgia, HA, asthenia
  53. Cymbalta
    • duloxetine
    • Antidepressant
    • SNRI
    • inhibits norepinephrine and serotonin reuptake
    • BBW: Increased risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: dizziness, HA, N/Vfatigue, xerostomia
  54. Deltasone
    • prednisolone
    • Anti-inflammatory
    • corticosteroids
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: osteoporosis, hypertension
  55. Depakote
    • divalproex
    • Antiepileptic/Antipsychotic
    • increases GABA effects, may inhibit glutamate/NMDA receptor-mediated neuronal excitation
    • SE: abdominal pain, diarrhea, nausea, vomiting, dizziness, somnolence, asthenia
    • BBW: hepatotoxicity
  56. Desyrel
    • trazadone
    • Antidepressant
    • increases GABA effects, may inhibit glutamate/NMDA receptor-mediated neuronal excitation
    • BBW: Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: xerostomia, HA, dizziness, fatigue, somnolence
  57. Detrol
    • tolterodine
    • Urinary bladder modifier
    • Anticholinergic
    • antagonizes acetylcholine receptors
    • SE: xerostomia, HA, constipation
  58. Diflucan
    • fluconazole
    • Antifungal
    • Candidiasis
    • inhibits cytochrome p450 and sterol C-14 alpha-demethylation
    • SE: HA, N/V
  59. Dilantin
    • phenytoin
    • Antiseizure
    • modulates neuronal voltage-dependent sodium and calcium channels
  60. Diovan-HCT
    • valsartan + HCT
    • Antihypertensive
    • ARB/Thiazide combos
    • BBW: fetal death
    • SE: nasopharingitis, increased BUN
  61. Diovan
    • valsartan
    • Antihypertensive
    • ARBs
    • selectively antagonizes angiotensin II AT1 receptors
    • BBW: fetal death
    • SE: hypotension, HA, increased BUN, dizziness
  62. Ditropan
    • oxybutynin
    • Antispasmodics
    • Anticholinergic
    • antagonizes acetylcholine at muscarinic receptors; relaxes bladder smooth muscle, inhibits involuntary detrusor muscle contractions
    • SE: pruritis, xerostomia, rash, constipatio, diarrhea
  63. Drisdol
    • ergocalciferol
    • Vitamin D
    • stimulates intestinal calcium and phosphorus absorption; stimulates bone mineralization
    • SE: hypercalcemia, renal impairment, calcification of soft-tissue, growth retardation
  64. DuoNeb
    • ipratropium + albuterol
    • Antiasthmatic
    • Beta-2 Agonists: Short-acting Inhaled; Anticholinergics, Inhaled
    • SE: bronchitis, upper resp infect, HA
  65. Duragesic
    • fentanyl
    • Opioid analgesic
    • binds to various opioid receptors, producing analgesia and sedation
    • BBW: fatal resp depression
  66. Dyazide
    • triamtrene/HCTZ
    • Antihypertensive
    • K+ sparing + thiazide diuretic
    • BBW: hyperkalemia
    • SE: asthenia, dizziness, HA
  67. Bayer
    • aspirin
    • Antiplatelet
    • platelet inhibitor
    • SE: bleeding, gastric ulcer
  68. Effexor
    • venlafaxine
    • Antidepressant
    • SNRIs
    • inhibits norepinephrine, serotonin, and dopamine reuptake
    • BBW: Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: sweating, weight loss, constipation, loss of appetite, N/V, xerostomia, asthenia, dizziness, HA, somnolence
  69. Elavil
    • amitriptyline
    • Antidepressant
    • TCA
    • BBW: Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: weight gain, xerostomia, somnolence, HA, dizziness, blurred vision
  70. Estrace
    • estradiol
    • Estrogen hormone
    • binds to estrogen receptors, developing and maintaining female sex characteristics and reproductive systems
    • BBW: Estrogens increase the risk of endometrial cancer
  71. Evista
    • raloxifene
    • Osteoporosis agent
    • estrogen receptor modulator: selectively binds to estrogen receptors, inhibiting bone resorption and turnover
    • BBW: DVT, PE
    • SE: hot sweats, leg cramp
  72. Flagyl
    • metronidazole
    • H. pylori
    • Antibacterial/Antiprotozoal
    • disrupts DNA and inhibits nucleic acid synthesis
    • BBW: carcinogenic
    • SE: HA, N/V, dizziness, vaginal discharge
  73. Flomax
    • tamsulosin
    • BPH
    • alpha-1 selective blocker
    • selectively antagonizes prostate alpha-1a adrenergic receptors, relaxing smooth muscle and improving urine flow
    • SE: backache, rhinitis, abnormal ejaction, dizziness, HA,
  74. Flonase
    • fluticasone
    • Antiallergy
    • nasal spray, corticosteroids
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: bronchitis, Upper resp infect, throat irritation
  75. Flovent
    • fluticasone
    • Antiasthmatic
    • Corticosteroids
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: HA, upper resp infect, sinusitis
  76. Folic Acid
    • vitamin B9
    • Vitamins
    • participates in DNA synthesis and erythropoiesis
    • SE: confusion, loss of appetite
  77. Fosamax
    • alendronate
    • Osteoporosis agent
    • Bisphosphonates
    • inhibits osteoclast activity, reducing bone resorption and turnover
    • SE: fever, flu-like symptom
  78. Glucophage
    • metformin
    • Antidiabetic
    • biguanides
    • decreases hepatic glucose production and intestinal glucose absorption; increases insulin sensitivity
    • SE: diarrhea, flatulence, vomiting, nausea
    • BBW: lactic acidosis
  79. Glucotrol
    • glipizide
    • Antidiabetic
    • Sulfonylureas
    • stimulates pancreatic islet beta cell insulin release
    • SE: hypoglycemia, weight gain
  80. Glucovance
    • glyburide/metformin
    • Antidiabetic
    • sulfonylureas/biguanides
    • BBW: lactic acidosis
    • SE: lactic acidosis, jaundice, diarrhea, upper resp infection, GI
  81. Humalog
    • insulin lispro
    • Antidiabetic
    • insulin
    • stimulates peripheral glucose uptake, inhibits hepatic glucose production, inhibits lipolysis and proteolysis, regulating glucose metabolism
  82. Humulin N
    • insulin NPH
    • Antidiabetic
    • insulin
    • stimulates peripheral glucose uptake, inhibits hepatic glucose production, inhibits lipolysis and proteolysis, regulating glucose metabolism
  83. Microzide
    • hydrochlorothiazide
    • Antihypertension
    • Thiazide diuretic
    • inhibits sodium reabsorption in the distal tubules causing increased excretion of sodium & water as well as potassium & hydrogren ions
    • SE: orthostatic hypertension, hypotension, hypokalemia, anorexia
  84. Hytrin
    • terazosin
    • Antihypertensive/BPH
    • alpha-1 antagonist
    • antagonizes peripheral alpha-1 adrenergic receptors
  85. Hyzaar
    • losartan/HCTZ
    • Antihypertensive
    • ARB/Thiazide combos
  86. Imdur
    • isosorbide mononitrate
    • Antianginal
    • vasodilators/nitrates
    • stimulates cGMP production, resulting in vascular smooth muscle relaxation
  87. Inderal
    • propranolol
    • Antihypertensive
    • Non-selective Beta-Blocker
    • non-selectively antagonizes beta-1 & beta-2 adrenergic receptors
    • BBW: Reports of exacerbation of angina and myocardial infarction have been noted following abrupt discontinuance of propranolol
    • SE: dizziness, fatigue, CHF, heart block, asthma, bronchospasm
  88. Calan
    • verapamil
    • Antihypertensive/Antiaginal
    • non-dihydropyridines CCBs
    • inhibits calcium ion influx into vascular smooth muscle and myocardium
    • SE: edema, hypotension, dizziness, HA, sinusitis, flu-like sumptoms
  89. Januvia
    • sitagliptin
    • Antidiabetic
    • DPP-4 Inhibitor
    • inhibits dipeptidyl peptidase-4, slowing incretin metabolism, increasing insulin synthesis/release, decreasing glucagon levels
    • SE: pancreatitis, upper respiratory infection, nasopharyngitis
  90. Keflex
    • cephalexin
    • Antibiotic
    • cephalosporins, 1st Gen
    • bactericidal; inhibits cell wall mucopeptide synthesis
  91. Kenalog
    • triamcinolone topical
    • Topical corticosteroids
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: HA, pharyngitis, flu-like symptoms, Cushing's syndrome
  92. Keppra
    • levetiracetam
    • Antiseizure
    • Anticonvulsant
    • SE: somnolence, depression, pharyngitis
  93. Klonopin
    • clonazepam
    • Antiepileptic
    • BZDs - Long-acting
    • binds to benzodiazepine receptors; enhances GABA effects
  94. Lamictal
    • lamotrigine
    • Antiepileptic
    • bipolar/seizure disorder
    • SE: nausea, vomiting, blurred vision
    • BBW: life-threatening rash
  95. Lanoxin
    • digoxin
    • inotropes/pressors
    • inhibits sodium-potassium ATPase
  96. Lantus
    • insulin glargine
    • Antidiabetes
    • insulin
    • stimulates peripheral glucose uptake, inhibits hepatic glucose production, inhibits lipolysis and proteolysis, regulating glucose metabolism
  97. Lasix
    • furosemide
    • Antihypertensive
    • Loop diuretic
    • inhibits loop of Henle and proximal and distal convoluted tubule sodium and chloride resorption
    • BBW: Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion.
    • SE: hyperuricemia, hypomagnesemia
  98. Levaquin
    • levofloxacin
    • Antibiotics
    • fluoroquinolones
    • bactericidal; inhibits DNA gyrase and topoisomerase IV
    • SE: QT prolongation, altered mental status,
    • BBW: Tendonitis/Tendon Rupture
  99. Levitra
    • vardenafil
    • Erectile dysfunction
    • inhibits phosphodiesterase type 5, enhancing effects of nitric oxide-activated increases in cGMP
  100. Lexapro
    • escitalopram
    • Antidepressant
    • SSRIs
    • selectively inhibits serotonin reuptake
  101. Lidoderm
    • lidocaine topical
    • Analgesics, local - minor cuts & burns
    • inhibits Na ion channels, stabilizing neuronal cell membranes and inhibiting nerve impulse initiation and conduction
  102. Lioresal
    • baclofen
    • Muscle relaxants
    • inhibits monosynaptic and polysynaptic spinal reflexes (centrally-acting muscle relaxant)
  103. Lipitor
    • atorvastatin
    • Antihyperlipidemia
    • HMG-CoA inhibitor
    • inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase
    • SE: rhabdomyalgia, diarrhea, UTI, nasopharyngitis
  104. Lodine
    • etodolac
    • NSAIDs
    • exerts anti-inflammatory, analgesic, and antipyretic effects by inhibiting prostaglandin synthesis
    • BBW: cardiovascular thrombotic, MI, & stroke, ulceration & stomach/intestine perforation
    • SE: edema, GI bleed
  105. Loestrin 24 Fe
    • norethindrone/ethinyl estradiol/ferrous fumarate
    • Oral contraceptive
    • suppresses LH & FSH, inhibiting ovulation; alters cervical mucus & endothelium
    • BBW: cigarrette smoking increases the risk of serious cardiovascular SE from oral contraceptive use
    • SE: edema, breakthrough-bleeding, breast tenderness, infertility
  106. Lopid
    • gemfibrozil
    • Antihyperlipidemia
    • Fibrates
    • inhibits peripheral lipolysis; decreases hepatic free fatty acid extraction; inhibits synthesis and increases clearance of VLDL carrier apolipoprotein B; mechanism of increased HDL unknown
    • SE: abdominal pain, indigestion
  107. Lopressor
    • metoprolol tartrate
    • Antihypertensive
    • Selective beta-1 blocker
    • selectively antagonizes beta-1 adrenergic receptors
    • BBW: Avoid Abrupt Cessation d/t sever angina exacerbation, MI, & ventricular arrhythmias - taper over 1-2wk
    • SE: hypotension, fatigue, dizziness, HF, bradyarrhythmia
  108. Lortab, Vicodin
    • hydrocodone/acetaminophen
    • Pain managment
    • Opioid analgesic
    • acetaminophen MOA unknown, produces analgesia and anti-pyretic effects; hydrocodone binds to various opioid receptors, producing analgesia and sedation
    • SE: drowsiness, sedated, respiratory depression
  109. Lotensin
    • benazapril
    • Antihypertensive
    • ACE inhibitor
    • inhibits angiotensin converting enzyme, interfering w/ conversion of angiotensin I to angiotensin II
    • BBW: can cause injury or death to fetus
    • SE: dizziness, HA, cough
  110. Lotrel
    • amlodipine/benazepril
    • Antihypertensive
    • CCB/ACE-inhibitor
    • BBW: can cause fetal death
    • SE: edema, cough
  111. Lotrisone
    • clotrimazole/betamethasone
    • Topical antifungal
    • antifungal/corticosteroids
    • SE: paresthesia, dry skin, sensation of burning
  112. Lovaza
    • omega-3 FAs
    • Antihyperlipidemia
    • reduces hepatic triglyceride synthesis
    • SE: burping, indigestion, taste altered
  113. Lumigan
    • bimatoprost ophthalmic
    • Agent for glaucoma
    • increases aqueous humor outflow
    • SE: dry eye, eye irritation, iris color change
  114. Lunesta
    • eszopiclone
    • Insomnia
    • interacts w/ GABA-benzodiazepine receptor complexes
    • SE: dizziness, HA, disorder of taste, respiratory tract infection
  115. Lyrica
    • pregabalin
    • Anti-seizure/Anti-neuralgic
    • binds alpha2-delta subunit of calcium channels reducing neurotransmitter release; produces antinociceptive and antiseizure effects
    • SE: dizziness, blurred vision, somnolence, tremor
  116. Macrobid
    • nitrofurantoin
    • Antibacterial
    • bactericidal or bacteriostatic; interferes w/ metabolism and inhibits protein and cell wall synthesis
    • SE: loss of appetite, N/V
  117. Medrol
    • methylprednisolone
    • Corticosteroids, systemic
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: hypertension, hyperglycemia, osteoporosis
  118. Dolophine, Methadose
    • methadone
    • Opioid analgesic, Opioid Addiction Tx
    • binds to various opioid receptors, producing analgesia and sedation (opioid agonist)
    • BBW: incomplete cross-tolerance, resp depression, QT prolongation
    • SE: constipation, n/v, dizziness, sedated, hypotension, respiratory depression
  119. Mevacor
    • lovastatin
    • Antihyperlipidemia
    • HMG-CoA
    • inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase
    • SE: abdominla pain, constipation, rhabdomyolysis
  120. Micardis
    • telmisartan
    • Antihypertensive
    • ARBs
    • selectively antagonizes angiotensin II AT1 receptors
    • BBW: fetal death
    • SE: upper respiratory infection
  121. DiaBeta
    • glyburide
    • Antidiabetic
    • Sulfonylureas
    • stimulates pancreatic islet beta cell insulin release
    • SE: hypoglycemia, cholestatic jaundice syndrome
  122. Minocin
    • minocycline
    • Antibiotics
    • Tetracyclines
    • bacteriostatic; inhibits protein synthesis
    • SE: dizziness, tooth discolored
  123. Miralax, Glycolax
    • polyethylene glycol 2250
    • Constipation
    • Osmotic laxative
    • causes water retention in stool, producing laxative effect
    • SE: diarrhea, flatulence, stomach cramps
  124. Mobic
    • meloxicam
    • NSAIDs
    • inhibits cyclooxygenase, reducing prostaglandin and thromboxane synthesis
    • BBW: risk of CV thrombotic event, MI, stroke - also stomach/intestine perforation
    • SE: edman, upper respiratory infection, indigestion, n/v, bleeding
  125. Motrin
    • ibuprofen
    • NSAIDs
    • inhibits cyclooxygenase, reducing prostaglandin and thromboxane synthesis
    • BBW: risk of CV thrombotic event, MI, stroke - also stomach/intestine perforation
    • SE: edman, upper respiratory infection, indigestion, n/v, bleeding
  126. MS Contin
    • morphine sulfate
    • Opioid analgesic
    • binds to various opioid receptors, producing analgesia and sedation
    • BBW: abuse potential, fatal respiratory depression if use 100-200mg ER in opioid-naive ptn
    • SE: N/V, constipation, dizziness, HA
  127. Robitussin AC
    • codeine/guaifenesin
    • Antitussive/Expectorant
  128. Namenda
    • memantine
    • Alzheimer Dz/Dementia
    • NMDA receptor antagonist
    • binds N-methyl-D-aspartate receptors, may slow Ca++ influx and nerve damage
    • SE: confusion, dizziness, HA
  129. Nasacort AQ
    • triamcinolone nasal
    • Antiallergy
    • Corticosteroid, nasal spray
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: pharyngitis, HA, influenza-like illness
  130. Nasonex
    • mometasone nasal
    • Antiallergy
    • Corticosteroid, nasal spray
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: HA, candidiasis
  131. Neurontin
    • gabapentin
    • Antiseizure
    • SE: somnolence, dizziness, ataxia, nystagmus
  132. Nexium
    • esomeprazole
    • Gastric antisecretory
    • PPIs; H. pylori
    • inhibits gastric parietal cell hydrogen-potassium ATPase
    • SE: diarrhea, abdominal pain
  133. Niaspan
    • niacin
    • Antihyperlipidemia
    • participates in tissue respiration oxidation-reduction reactions; decreases hepatic LDL and VLDL production; inhibits adipose tissue lipolysis; decreases hepatic triglyceride esterification; increases lipoprotein lipase activity
    • SE: flushing, N/V
  134. Nitrostat
    • nitroglycerin
    • Antianginal
    • Vasodilators
    • stimulates cGMP production, resulting in vascular smooth muscle relaxation
    • SE: headache, lighheadedness
  135. Nizoral
    • ketoconazole topical
    • Antifungal
    • Seborrhea/Dandruff
    • inhibits fungal cell membrane ergosterol synthesis
    • SE: burning sensation, pruritus
  136. Trandate
    • labetalol
    • Antihypertensive
    • Selective alpha & non-selective beta blocker
    • selectively antagonizes alpha-1 adrenergic receptors; antagonizes beta-1 and beta-2 adrenergic receptors
    • SE: orthostatic hypotension (IV), dizziness, fatigue, HA, N/V
  137. Norvasc
    • amlopidine
    • Antihypertensive/Angina/Prinzmetal's
    • DHP CCB
    • inhibits calcium ion influx into vascular smooth muscle and myocardium during depolarization, producing a relaxation of coronary vascular smooth muscle and coronary vasodilation; increases myocardial oxygen delivery in patients with vasospastic angina
    • SE: peripheral edema, HA, flushing
  138. Novolog
    • insulin aspart
    • Anti-diabetic (Type 1 & 2) - rapid-acting
    • stimulates peripheral glucose uptake, inhibits hepatic glucose production, inhibits lipolysis and proteolysis, regulating glucose metabolism
    • SE: hypoglycemia, weight gain, lipodystrophies
  139. NuvaRing
    • etonogestrel/ethinyl estradiol vaginal
    • Contraceptives
    • suppresses LH and FSH, inhibiting ovulation; alters cervical mucus and endometrium
    • BBW: Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptive use.
    • SE: weight gain, sinusitis, upper resp infection
  140. Nystop
    • nystatin
    • Antifungal antibiotic
    • Candidiasis
    • binds to cell membrane sterols, increasing permeability
    • SE: skin irritation, SJS
  141. Omnicef
    • cefdinir
    • Antibiotic
    • 3rd Gen Cephalosporin
    • bactericidal; inhibits cell wall mucopeptide synthesis
    • SE: diarrhea
  142. Orapred
    • prednisolone
    • Anti-inflammatory
    • Corticosteroids, systemic
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: hypertension, hyperglycemia, depression, mood swings
  143. Ortho-Cyclen
    • norgestimate/ethinyl estradiol
    • Oral contraceptives
    • Monophasic OCPs
    • suppresses LH and FSH, inhibiting ovulation; alters cervical mucus and endometrium
    • BBW: Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptive use.
    • SE: edema, weight gain
  144. Ogestrel
    • norgestrel/ethinyl estradiol
    • Oral contraceptives
    • Monophasic OCPs
    • suppresses LH and FSH, inhibiting ovulation; alters cervical mucus and endometrium
    • BBW: Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptive use.
    • SE: edema, weight gain
  145. OxyContin
    • oxycodone CR
    • Opioid analgesic
    • binds to various opioid receptors, producing analgesia and sedation (opioid agonist)
    • BBW: abuse potential, fatal resp depression
    • SE: somnolence, N/V, constipation
  146. Pamelor
    • nortriptyline
    • Antidepressant
    • TCA
    • inhibits norepinephrine and serotonin reuptake
    • BBW: increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: constipation
  147. Patanol
    • olopatadine ophthalmic
    • Anti-allergy
    • selectively antagonizes histamine H1 receptors; inhibits histamine release from mast cells
    • SE: altered tastse, HA, common cold
  148. Paxil
    • paroxetine
    • Antidepressant
    • SSRI
    • selectively inhibits serotonin reuptake
    • BBW: Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: constipation, diaphoresis, HA, somnolence, tremor, asthenia
  149. Pepcid
    • famotidine
    • Anti-ulcer agent
    • H2 blocker
    • selectively antagonizes histamine H2 receptors
    • SE: constipation, diarrhea, HA, dizziness
  150. Percocet
    • oxycodone/acetaminophen
    • Opioid analgesic
    • SE: dizziness, sedated, somnolence
  151. Phenergan
    • promethazine
    • Anti-emetic
    • 1st Gen Antihistamine
    • non-selectively antagonizes central and peripheral H1 receptors; possesses anticholinergic properties, resulting in antiemetic and sedative effects
    • BBW: IV injection can cause extravasation, the use in peds <2 y/o can cause resp depression
    • SE: depression, dizziness, sedated, somnolence
  152. Plaquenil
    • hydroxychloroquine
    • Anti-malarial
    • DMARDs
    • SE: disorder of cornea
  153. Plavix
    • clopidogrel
    • Antiplatelets/Stroke
    • Platelet inhibitor
    • irreversibly binds to adenosine diphosphate receptors, inhibiting platelet activation and aggregation
    • BBW: In patients who are CYP2C19 poor metabolizers, clopidogrel at recommended doses forms less of that metabolite and has a smaller effect on platelet function.
    • SE: bleeding
  154. Plendil
    • felodipine
    • Antihypertensive
    • DHP CCB
    • inhibits calcium ion influx into vascular smooth muscle and myocardium during depolarization, producing a relaxation of coronary vascular smooth muscle and coronary vasodilation; increases myocardial oxygen delivery in patients with vasospastic angina
    • SE: HA, peripheral edema, flushing, tachycardia
  155. Pravachol
    • pravastatin
    • Antihyperlipidemia
    • HMG-CoA reductase inhibitor
    • SE: musculoskeletal pain, upper resp infection, diarrhea, N/V
  156. Premarin
    • conjugated estrogens
    • Estrogen Hormone
    • binds to estrogen receptors, developing and maintaining female sex characteristics and reproductive systems
    • BBW: endometrial cancer
  157. Prevacid
    • lansoprazole
    • Gastric antisecretory
    • PPIs/H. pylori
    • inhibits gastric parietal cell hydrogen-potassium ATPase (proton pump inhibitor)
    • SE: diarrhea, constipation, abdominal pain
  158. Prilosec
    • omeprazole
    • Anti-ulcer agent
    • PPIs/H. pylori
    • inhibits gastric parietal cell hydrogen-potassium ATPase
    • SE: abdominal pain, diarrhea, HA
  159. Procardia
    • nifedipine
    • Antihypertensive/Antiaginal
    • DHP CCB
    • inhibits calcium ion influx into vascular smooth muscle and myocardium
    • SE: hypotension, peripheral edema, flushing, HA, dizziness
  160. Proscar
    • finasteride
    • BPH
    • Prostate anti-inflammatory
    • inhibits type II 5-alpha-reductase, interfering w/ conversion of testosterone to 5-alpha-dihydrotestosterone
    • SE: abnormal ejaculation, breast tenderness, reduced libidio
  161. Protonix
    • pantoprazole
    • Anti-ulcer agent
    • PPIs/H. pylori
    • inhibits gastric parietal cell hydrogen-potassium ATPase
    • SE: abdominal pain, diarrheam, HA
  162. Proventil HFA
    • albuterol inhaled
    • Anti-asthmatic
    • Beta-2 agonist; short-acting inhaled
    • stimulates beta-2 adrenergic receptors, relaxing airway smooth muscle (selective beta agonist)
    • SE: pharyngitis, throat irritation, rhinitis, upper resp infection, nausea
  163. Ventolin HFA
    • albuterol inhaled
    • Anti-asthmatic
    • Beta-2 agonist; short-acting inhaled
    • stimulates beta-2 adrenergic receptors, relaxing airway smooth muscle (selective beta agonist)
    • SE: pharyngitis, throat irritation, rhinitis, upper resp infection, nausea
  164. Prozac
    • fluoxetine
    • Antidepressant
    • SSRI
    • selectively inhibits serotonin reuptake
    • BBW: increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: insomnia, somnolence, rhinitis, loss of appetite
  165. Pyridium
    • phenazopyridine
    • Urinary tract analgesic
    • the precise mode of action is unknown but when excreted in the urine, it promotes topical analgesia on the mucosa of the urinary tract, thus relieving pain, burning, urgency and frequency
    • SE: HA
  166. Reglan
    • metoclopramide
    • Anti-emetic
    • sensitizes tissues to acetylcholine, stimulating upper GI tract motility; antagonizes central and peripheral dopamine receptors, producing antiemetic effects
    • BBW: tardive dyskinesia
    • SE: asthenia, HA, somnolence, fatigue
  167. Relafen
    • nabumetone
    • NSAIDs
    • inhibits cyclooxygenase, reducing prostaglandin and thromboxane synthesis
    • BBW: risk of CV thrombotic event, MI, stroke - also stomach/intestine perforation
    • SE: edman, upper respiratory infection, indigestion, n/v, bleeding
  168. Remeron
    • mirtazapine
    • Antidepressant
    • Tetracyclic
    • antagonizes alpha-2 adrenergic and serotonin 5-HT2 receptors
    • BBW: increased the risk of suicidal thinking and behavior in children, adolescents, and young adults
    • SE: weight gain, somnolence, xerostomia, dizziness
  169. Requip
    • ropinirole
    • Anti-Parkinson/Dystonia
    • Dopamine agonist
    • stimulates dopamine receptors
    • SE: dizziness, N/V, HA
  170. Restoril
    • temazepam
    • Sedative/Insomnia
    • BZDs; Mid-acting
    • binds to benzodiazepine receptors; enhances GABA effects
    • SE: somnolence, blurred vision
  171. Risperdal
    • risperidone
    • Bipolar Disorder
    • Antipsychotics, 2nd generation
    • antagonizes dopamine D2 receptors, serotonin 5-HT2 receptors
    • BBW: Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo.
  172. Robaxin
    • methocarbamol
    • Muscle relaxant
    • SE: dizziness, HA, nystagmus, somnolence, vetigo
  173. Seroquel
    • quetiapine
    • Bipolar
    • Atypical Antipsychotic, 2nd Gen
    • antagonizes dopamine D2 receptors, serotonin 5-HT2 receptors
    • BBW: Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo.
  174. Singulair
    • montelukast
    • Antiasthmatic
    • Leukotriene inhibitor
    • selectively binds to cysteinyl leukotriene receptors
    • SE: headache
  175. Skelaxin
    • metaxalone
    • Muscle relaxant
    • centrally-acting muscle relaxant
    • SE: dizziness, HA, somnolence, N/V
  176. Soma
    • carisoprodol
    • Muscle relaxant
    • centrally-acting muscle relaxant
    • SE: somnolence, dizziness, HA
  177. Spiriva
    • tiotropium inhaled
    • Antiasthmatic
    • Anticholinergic
    • antagonizes acetylcholine receptors, producing bronchodilation
    • SE: xerostomia, pharyngitis, sinusitis, upper resp infection
  178. Suboxone
    • buprenorphine/naloxone
    • Opioid Dependence
    • SE: sweating, constipation, N/V, HA, vasodilation, pain
  179. Synthroid
    • levothyroxine
    • Hypothyroidism
    • Synthetic T4
    • produces various physiologic effects, including increasing metabolism
    • BBW: not for weight loss treatment
    • SE: MI, liver failure, seizure
  180. Tamiflu
    • oseltamivir
    • Antiviral
    • Tx of acute illness d/t influenza A or B
    • inhibits influenza neuraminidase
    • SE: abdominal pain, N/V
  181. Temovate
    • clobetasol topical
    • Anti-inflammatory, topical
    • Corticosteroids - highest potency
    • inhibits multiple inflammatory cytokines; produces multiple glucocorticoid and mineralocorticoid effects
    • SE: nasopharyngitis, upper resp infection
  182. Tenoretic
    • atenolol/chlorthalidone
    • Antihypertensive
    • Selective B-blocker + thiazide diuretic
    • SE: hypotension, dizziness, fatigue, HA, dyspnea
  183. Tenormin
    • atenolol
    • Anti-HTN/Anti-angina/post-MI
    • Selective Beta-blocker
    • selectively antagonizes beta-1 adrenergic receptors
    • BBW: BB therapy should not be withdrawn abruptly (particularly in patients with CAD), but gradually tapered to avoid acute tachycardia, HTN, & ischemia
    • SE: bradycardia, cold extremities, hypotension, dizziness, depression, fatigue
  184. Tessalon
    • benzonatate
    • Anticough
    • Antitussive
    • anesthetizes respiratory passage, lung, and pleural stretch receptors, reducing cough reflex
    • SE: oral hypoesthesia if capsule broken, dizziness, HA, sedated, somnolence
  185. Topamax
    • topiramate
    • Antiseizure/migraine/HA
    • SE: dizzines, impaired psychomotor performance, paresthesia, somnolence, fatigue
  186. Toprol-XL
    • metoprolol succinate
    • Antihypertensive
    • Selective B-1 blocker
    • selectively antagonizes beta-1 adrenergic receptors
    • BBW: Following abrupt cessation of therapy with certain beta-blocking agents, exacerbations of angina pectoris and, in some cases, myocardial infarction have occurred
    • SE: dizziness, fatigue, pruritus
  187. Tricor
    • fenofibrate
    • Antihyperlipidemia
    • Activate PPARa
    • inhibits triglyceride synthesis and stimulates catabolism of triglyceride-rich lipoproteins (fibric acid derivative)
    • SE: backache, abdominal pain, AST/liver function test abnormal
  188. Tussionex
    • chlorpheniramine/hydrocodone
    • Antitussive
    • Antihistamine/Antitussive combos
    • chlorpheniramine antagonizes central and peripheral H1 receptors, drying nasal and sinus passages (non-selective antihistamine); hydrocodone binds to various opioid receptors, producing analgesia, sedation and antitussive effects (opioid agonist)
    • SE:
  189. Ultracet
    • tramadol/acetaminophen
    • Analgesic
    • BBW: APAP can cause liver toxicity if > 4g/d
    • SE: somnolence, constipation, xerostomia, dizziness
  190. Ultram
    • tramadol
    • Opioids analgesic
    • binds to mu opioid receptors and weakly inhibits norepinephrine/serotonin reuptake, producing analgesia
    • SE: dizziness, drowsiness, somnolence, HA, constipation, nausea
  191. Valium
    • diazepam
    • Antianxiety/Antiseizure/Alcohol dependence
    • BZDs - long acting
    • binds to benzodiazepine receptors; enhances GABA effects
  192. Valtrex
    • valacyclovir
    • Antiviral
    • Herpes/Varicella/Zoster
    • inhibits DNA polymerase; incorporates into viral DNA
    • SE: HA, rash, N/V
  193. Vasotec
    • enalapril
    • Antihypertensive
    • ACE-Inhibitor
    • inhibits angiotensin converting enzyme, interfering w/ conversion of angiotensin I to angiotensin II
    • BBW: fetal death
    • SE: cough, hypotension, dizziness, elevated BUN/SCr, hyperkalemia
  194. Pen VK
    • penicillin V potassium
    • Antibiotic, PCN
    • Tx of respiratory tract, otitis media, sinusitis, skin, UTI
    • inhibits bacterial cell wall synthesis by binding to one or more of the penicillin binding proteins (PBPs)
    • SE: diarrhea, N/V, oral candidiasis
  195. Viagra
    • sildenafil
    • Erectile dysfunction
    • Phosphodiesterase-5 Enzyme
    • inhibits phosphodiesterase type 5, enhancing effects of nitric oxide-activated increases in cGMP
    • SE: HA, dyspepsia, flushing
  196. Vibramycin
    • doxycycline
    • Tetracycline abx
    • inhibits protein synthesis by binding with the 30S & 50S ribosomal subunits
    • SE: anorexia, yellow teeth, bone suppression, photosensitivity
  197. Vigamox
    • moxifloxacin ophthalmic
    • Fluoroquinolone abx
    • Tx of bacterial conjunctivitis
  198. Voltaren
    • diclofenac ophthalmic
    • NSAIDs
    • Post-operative inflammation following cataract extraction; temporary relief of pain
  199. Vytorin
    • ezetimibe/simvastatin
    • Antihyperlipidemia
    • inhibitor of intestinal absorption/HMG-CoA reductase inhibitor
  200. Wellbutrin
    • buPROPion
    • Antidepressant/Smoking Cessation Aid
    • Tx of MDD; smoking cessation
    • inhibits NE & dopamine uptake
    • BBW: depression & suicidal thoughts in smoking cessation; antidepressants increase risk of suicidal thinking in children & adolescent
    • SE: xerostomia, HA, dizziness, insomnia, weight loss, tachycardia
  201. Xanax
    • alprazolam
    • Antianxiety
    • BZDs; short-acting
    • Restriction: C-IV
    • binds to benzodiazepine receptors; enhances GABA effects
    • SE: drowsiness, fatigue, memory impairment, sedation, somnolence, cognitive disorder
  202. Xopenex
    • levalbuterol
    • Antiasthmatic
    • Beta-2 agonist; short-acting
    • relaxes bronchial smooth muscle by action of beta-2-receptors with little effect on the heart
    • SE: increases serum glucose, hypokalemia, tremor, rhinitis
  203. Ocella / Yasmin / Yaz
    • ethinyl estradiol/drospirenone
    • Oral contraceptive
    • Estrogen & Progestin combination
    • Prevention of pregnancy; tx of PMDD; tx of acne
    • suppresses LH & FSH, inhibiting ovulation; alters cervical mucus & endometrium
    • BBW: smoking increases risk of serious CV events
  204. Zanaflex
    • tiZANidine
    • Centrally-acting muscle relaxant
    • Alpha-2-Adrenergic agonist
    • an alpha2-adrenergic agonist agent which decreases excitatory input to alpha motor neuron
    • SE: hypotension, somnolence, dizziness, xerostomia, weakness
  205. Zantac
    • ranitidine
    • Anti-ulcer agent/GERD
    • Histamine-H2 antagonist
    • inhibition of histamin at H2-receptors of the gastric parietal cells, which inhibits gastric acid secretion, gastric volume, & hydrogen ion concentration are reduced
    • SE: constipation, diarrhea, abdominal pain, HA
  206. Zebeta
    • bisoprolol
    • Antihypertensive
    • Beta-Blocker, Selective Beta-1
    • selectively antagonizes beta-1 adrenergic receptors
    • SE: fatigue, HA
  207. Zestril / Prinivil
    • lisinopril
    • Antihypertensive
    • ACE Inhibitor
    • inhibits angiotensin converting enzyme, interfering w/ conversion of angiotensin I to angiotensin II
    • BBW: fetal/neonatal morbidity/mortality may occur when drugs that act directly on the renin-angiotensin system are used in pregnancy
    • SE: hypotension, HA, dizziness, cough, hyperkalemia, BUN/SCr increase
  208. Zestoretic / Prinzide
    • lisinopril + HCTZ
    • Antihypertensive
    • ACE Inhibitor/Diuretic
    • BBW: fetal/neonatal morbidity/mortality may occur when drugs that act directly on the renin-angiotensin system are used in pregnancy
    • SE: hypotension, HA, dizziness, cough, hyperkalemia, BUN/SCr increase
  209. Zetia
    • ezetimibe
    • Antihyperlipidemic
    • inhibits intestinal absorption of cholesterol; leads to a decreased delivery of cholesterol to the liver; decrease TC, TG, LDL but increase HDL
    • SE: upper resp infection, arthralgia
  210. Ziac
    • bisoprolol + HCT
    • Antihypertensive
    • Selective Beta-1/Thiazide diuretic
  211. Zithromax / Z-pack
    • azithromycin
    • Macrolide antibiotic
    • Otitis media, bacterial sinusitis, CA-pneumonia, SST, PID
    • bacteriostatic; binds to P site of 50S ribosomal subunit, interfering w/ protein synthesis
    • SE: diarrhea, N/V
  212. Zocor
    • simvastatin
    • Antihyperlipidemic
    • HMG-CoA reductase inhibitor - the rate limiting step in cholesterol biosynthesis
    • BBW: rhabdomyolysis - starting dose is 40mg; patient must be on the drug at least 1 year in order to be on 80mg
    • SE: creatine kinase level increase, resp infection, abd pain, constipation
  213. Zoloft
    • sertraline
    • Antidepressant
    • SSRI
    • selectively inhibits serotonin reuptake
    • BBW: Suicidality -incr. suicidality risk in children, adolescents, and young adults w/ major depressive or other psychiatric disorders
    • SE: sexual dysfunction, drowsiness, weight gain, HA, somnolence
  214. Zovirax
    • acyclovir
    • Antiviral
    • Tx of genital herpes simplex virus (HSV)
    • inhibits DNA polymerase; incorporates into viral DNA
    • SE: malaise
  215. Zyloprim
    • allopurinol
    • Agent for gout/nephropathy/hyperuricemia
    • Xanthine Oxidase Inhibitor
    • inhibits xanthine oxidase, interfering w/ conversion of hypoxanthine and xanthine to uric acid
  216. Zyprexa
    • olanzapine
    • Antipsychotic
    • Tx of schizophrenia/mania/bipolar
    • antagonizes dopamine, serotonin 5-HT2
    • BBW: not approved for dementia-related psychosis; incr. mortality risk in elderly dementia pts on conventional or atypical antipsychotics;
    • SE: weight gain, somnolence, extrapyramidal, dyspepsia, dizziness

What would you like to do?

Home > Flashcards > Print Preview