Haloperidol

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Author:
junglejim
ID:
96480
Filename:
Haloperidol
Updated:
2011-08-09 00:41:29
Tags:
Haloperidol Haldol
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Description:
paramedic Haldol
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  1. Haldol Class:
    • High-potency antipsychotic
    • Major tranquilizer
  2. Haldol Mechanism of Action:
    • Blocks postsynaptic dopamine receptors (D2) in the mesolimbic system (associated with mood & behavior).
    • The decrease in dopamine neurotransmission has been found to correlate with the antipsychotic effects.
    • Haloperidol possesses extremely weak anticholinergic and alphaadrenergic receptor blocking effects
  3. Haldol Indications:
    Acute Psychosis (Consideration for patient & rescuer safety)
  4. Haldol Contraindications:
    • Coma
    • Severe toxic CNS depression
    • Parkinson's disease (dopamine blockade can dramatically worsen the condition)
  5. Haldol Precautions:
    • Severe cardiovascular disorders (EKG monitoring is recommended in these patients)
    • Pregnancy (C)
    • Seizure disorder (slight lowering of seizure threshold)
    • Elderly patients may require reduce dosage
  6. Haldol Dosage Adults:
    5-10 mg IV or IM maximum dosage 20 mg (reduce dosage to 0.5 to 2 mg in geriatrics)
  7. Haldol Dosage Peds:
    • 0.5 mg IM (Not covered in ACEMSS SWO’s)
    • One reference suggested in children 6-12 years of age: 1-3 mg IV or IM (Not covered in ACEMSS SWO’s)
  8. Haldol Onset:
    • IM—10-20 minutes (one reference suggests 30-60 minutes)
    • IV—Data not available since it is not an FDA approved use
  9. Haldol Duration:
    12-24 hours
  10. Haldol Side Effects:
    • Extrapyramidal reactions
    • Neuroleptic malignant syndrome (hyperthermia, severe extrapyramidal dysfunction, alterations in consciousness, altered mental status, and autonomic instability)
    • Orthostatic hypotension
    • Insomnia, restlessness
    • Sedation
    • Seizures
    • Respiratory depression
    • Anticholinergic effects
    • Tachycardia
  11. Haldol Interactions:
    • Additive effects—may induce hypotension in patients taking antihypertensives
    • May decrease the activity of warfarin
    • Patients taking lithium may develop encephalopathic syndrome

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