New Medications

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  1. Generic name of Durezol
    difluprednate ophthalmic emulsion
  2. Durezol class and indications
    topical ophthalmic corticosteroid indicated for the treatment of inflammation and pain associated with ocular surgery
  3. How did difluprednate compare to pred forte for anterior uveitis
    This study shows that Durezol is a potent steroid that can be used effectively four times a day to reduce inflammation in patients with moderate to severe uveitis. Compared to 8 times per day for Pred Forte.
  4. How is Durezol chemically different from pred forte
    Difluorinated prednisolone derivative to increase the potentency of anti-inflammatory activity

    F - prednisolone - F
  5. Contraindications to Durezol
    viral diseases/bacteria/fungal infections of the cornea/conjunctiva
  6. Generic name if Latuda
  7. Class of lurasidone
    atypical antipsychotic
  8. Why is Latuda considered to be useful for treating the cognative and memory deficits seen in schizophrenia
    1) unlike many other antipsychotics, lurasidone does not block the muscarinic acetylcholine receptors, an action well-known to impair learning and memory

    2) lurasidone has prominent activity at 5-HT1A, 5-HT2A, 5-HT7, and α2C-adrenergic receptors, all of which have been implicated in enhancement of cognitive function if modulated properly

    3) due to its low liability for extrapyramidal symptoms, lurasidone is unlikely to require coadministration of anticholinergics, which impair cognition in their own right
  9. Generic name of Viibyrd
  10. Pharmacology of vilazodone
    serotonin reuptake inhibitor and 5-HT1A receptor partial agonist
  11. What makes vilazodone pharmacologically different from other medication
    Partial agonism of the 5-HT1A receptor is a relatively novel mechanism of action and is also shared by the anxiolytic buspirone (Buspar), and the atypical antipsychotic / antidepressant aripiprazole (Abilify)
  12. Why would you select Vilazodone over other antidepressants for a patient
    When sexual dysfunction is a concern

    Specifically the incidence of orgasmic dysfunction in women and ejaculatory delay or dysfunction in men was less than 3% and very near the rates with placebo

    • Other antidepressants have a rate
    • >15%
  13. What is are the disadvanges of using vilazodone over other antidepressants
    1) higher incidence of gastrointestinal side effects than most of the SSRIs

    2) generic SSRIs are available

    This will probably be a secondary agent for those who have sexual side effects from other antidepressants
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New Medications
2011-08-20 01:02:06
new medications medication trivia

New medication trivia
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