Cardio Drugs - Hypertension

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Author:
coletrain3
ID:
98028
Filename:
Cardio Drugs - Hypertension
Updated:
2011-08-23 01:51:19
Tags:
Cardio drugs cardiovascular hypertension HTN
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Description:
Cardio drugs used to treat Hypertension
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  1. HTN - Thiazide Diruetics
    • Hydrochlorothiazide (HCTZ)
    • Chlorthalidone
    • Metolazone (Zaroxolyn)
  2. HTN - Loop Diruetics
    • Bumetanide (Bumex)
    • Furosemide (Lasix)
    • Torsemide (Demadex)
  3. HTN - Aldosterone Antagonists
    • Spironolactone (Aldactone)
    • Eplerenone (Inspra)
  4. HTN - Selective Beta Blockers
    • Atenolol (Tenormin)
    • Bisoprolol (Zebeta)
    • Metoprolol (Lopressor)
    • Metoprolol ER (Toprol XL)
    • Nebivolol (Bystolic)
  5. HTN - Alpha/Beta Blockerts
    • Carvedilol (Coreg)
    • Labetalol (Trandate)
  6. HTN - ACE Inhibitors
    • Benazepril (Lotensin)
    • Captopril (Capotin)
    • Enalapril (Vasotec)
    • Fosinopril (Monopril)
    • Lisinopril (Prinvil, Zestril)
    • Moexipril (Univasc)
    • Perindopril (Aceon)
    • Quinapril (Accupril)
    • Ramipril (Altace)
    • Trandolapril (Mavik)
  7. HTN - ARBs (Angiotensin II Receptor Blockers)
    • Azilsartan (Edarbi)
    • Candesartan (Atacand)
    • Eprosartan (Teveten)
    • Irbesartan (Avapro)
    • Losartan (Cozaar)
    • Olmesartan (Benicar)
    • Telmisartan (Micardis)
    • Valsartan (Diovan)
  8. HTN - Calcium Channel Blockers - Non-dihydropyridines
    • Diltiazem ER (Cardizem CD, Cardizem LA, Dilacor XR, Tiazac)
    • Verapamil IR (Calan, Isoptin)
    • Verapamil LA (Calan SR, Isoptin SR)
    • Verapamil coer (Covera HS, Verelan PM)
  9. HTN - Calcium Channel Blockers - Dihydropyridines
    • Amlodipine (Norvasc)
    • Felodipine (Plendil)
    • Isradipine (Dynacirc SR)
    • Nicardipine SR (Cardene SR)
    • Nifedipine LA (Adalat CC, Procardia XL)
    • Nisoldipine (Sular)
  10. HTN - Centrally Acting
    • Clonidine (Catapres)
    • Clonidine Patch (Catapres TTS)
    • Methyldopa (Aldomet)
  11. HTN - Direct Vasodilators
    Hydralazine (Apresoline)
  12. HTN - Direct Renin Inhibitors
    Aliskerin (Tekturna)
  13. Hydrochlorothiazide (HCTZ)
    • Dosing Range: 12.5-25mg
    • Frequency: 1
  14. Chlorthalidone
    • Dosing Range: 12.5-25mg
    • Frequency: 1
  15. Metolazone
    • Dosing Range: 2.5-5mg
    • Frequency: 1
  16. Bumetanide
    • Dosing Range: 0.5-2mg
    • Frequency: 2
  17. Furosemide
    • Dosing Range: 20-80mg
    • Frequency: 2
  18. Torsemide
    • Dosing Range: 2.5-10mg
    • Frequency: 1
  19. Spironolactone
    • Dosing Range: 50-100mg
    • Frequency: 1 to 2
  20. Eplerenone
    • Dosing Range: 25-50mg
    • Frequency: 25-50mg
  21. Atenolol
    • Dosing Range: 25-100mg
    • Frequency: 1
  22. Bisoprolol
    • Dosing Range: 2.5-10mg
    • Frequency: 1
  23. Metoprolol
    • Dosing Range: 50-100mg
    • Frequency: 2
  24. Metoprolol ER
    • Dosing Range: 50-100mg
    • Frequency: 1
  25. Nebivolol
    • Dosing Range: 2.5-40mg
    • Frequency: 1
  26. Carvedilol
    • Dosing Range: 12.5-50mg
    • Frequency: 2
  27. Labetalol
    • Dosing Range: 200-800mg
    • Frequency: 2
  28. Benazepril
    • Dosing Range: 10-40mg
    • Frequency: 2
  29. Captopril
    • Dosing Range: 25-100mg
    • Frequency: 2
  30. Enalapril
    • Dosing Range: 2.5-40mg
    • Frequency: 1 to 2
  31. Fosinopril
    • Dosing Range: 10-40mg
    • Frequency: 1
  32. Lisinopril
    • Dosing Range: 10-40mg
    • Frequency: 1
  33. Moexipril
    • Dosing Range: 7.5-30mg
    • Frequency: 1
  34. Perindopril
    • Dosing Range: 4-8mg
    • Frequency: 1 to 2
  35. Quinapril
    • Dosing Range: 10-40mg
    • Frequency: 1
  36. Ramipril
    • Dosing Range: 2.5-20mg
    • Frequency: 1
  37. Trandolapril
    • Dosing Range: 1-4mg
    • Frequency: 1
  38. Azilsartan
    • Dosing Range: 40-80mg
    • Frequency: 1
  39. Candesartan
    • Dosing Range: 8-32mg
    • Frequency: 1
  40. Eprosartan
    • Dosing Range: 400-800mg
    • Frequency: 1 to 2
  41. Irbesartan
    • Dosing Range: 150-300mg
    • Frequency: 1
  42. Losartan
    • Dosing Range: 25-100mg
    • Frequency: 1 to 2
  43. Olmesartan
    • Dosing Range: 20-40mg
    • Frequency: 1
  44. Telmisartan
    • Dosing Range: 20-80
    • Frequency: 1
  45. Valsartan
    • Dosing Range: 80-320mg
    • Frequency: 1
  46. Diltiazem extended release (Cardizem CD, Dilacor XR, Tiazac)
    • Dosing Range: 180-420mg
    • Frequency: 1
  47. Diltiazem extended release (Cardizem LA)
    • Dosing Range: 120-540mg
    • Frequency: 1
  48. Verapamil immediate release
    • Dosing Range: 80-320mg
    • Frequency: 2
  49. Verapamil long-acting
    • Dosing Range: 120-360mg
    • Frequency: 1-2
  50. Verapamil - coer
    • Dosing Range: 120-360mg
    • Frequency: 1
  51. Amlodipine
    • Dosing Range: 2.5-10mg
    • Frequency: 1
  52. Felodipine
    • Dosing Range: 2.5-20mg
    • Frequency: 1
  53. Isradipine
    • Dosing Range: 2.5-10mg
    • Frequency: 2
  54. Nicardipine SR
    • Dosing Range: 60-120mg
    • Frequency: 2
  55. Nifedipine long-acting
    • Dosing Range: 30-60mg
    • Frequency: 1
  56. Nisoldipine
    • Dosing Range: 10-40mg
    • Frequency: 1
  57. Clonidine
    • Dosing Range: 0.1-0.8 mg
    • Frequency: 2
  58. Clonidine patch
    • Dosing Range: 0.1-0.8mg
    • Frequency: Weekly
  59. Methyldopa
    • Dosing Range: 250-1,000mg
    • Frequency: 2
  60. Hydralazine
    • Dosing Range: 25-100mg
    • Frequency: 2
  61. Aliskerin
    • Dosing Range: 150-30
    • Frequency: 2
  62. What is the MOA of Thiazide Diuretics?
    Inhibits the Na+/Cl- transporter in the Distal Convoluted Tubule.
  63. What are some adverse effects of Thiazide Diuretics?
    • Electrolyte disturbance
    • Orthostasis
    • Dizziness
  64. How do you monitor Thiazide Diuretics?
    • BUN/SCr
    • electrolytes
  65. What is the MOA of Loop Diuretics?
    Inhibits Na+/K+/Cl- transporter in the ASCENDING loop of Henle.
  66. What are some adverse effects of Loop Diuretics?
    • Electrolyte disturbance
    • Orthostasis
    • Dizziness
  67. How do you monitor Loop Diuretics?
    • BUN/SCr
    • electrolytes
    • serum bicarbonate
    • may monitor CBC, Plt and LFTs
  68. What is the MOA of Aldosterone Antagonists?
    K+ sparing; antagonizes aldosterone receptor in DCT
  69. What are some adverse effects of Aldosterone Antagonists?
    • hyperkalemia
    • GI
    • gynecomastia
  70. How do you monitor Aldosterone Antagonists?
    • BUN/SCr
    • electrolytes

    *closely follow SCr, potassium
  71. What is the MOA of Selective Beta Blockers?
    Selectively antagonizes the beta-1 adrenoreceptor.
  72. What are some Adverse Effects of Selective Beta Blockers?
    • heart failure
    • heart block
    • depression
    • bradycardia
    • dyspnea (shortness of breath)
    • dizziness
    • fatigue
  73. How do you monitor Selective Beta Blockers?
    • BUN/SCr
    • HR
  74. What is the MOA of Alpha/Beta Blockers?
    Antagonizes alpha-1 and beta-1 adrenoreceptors
  75. What are some Adverse Effects of Alpha/Beta Blockers?
    • heart failure
    • heart block
    • depression
    • bradycardia
    • dyspnea (shortness of breath)
    • dizziness
    • fatigue
  76. How do you monitor Alpha/Beta Blockers?
    • BUN/SCr
    • HR
  77. What is the MOA of ACE Inhibitors?
    Inhibits the conversion of angiotensin I to angiotensin II.
  78. What are some Adverse Effects of ACE Inhibitors?
    • angioedema
    • hyperkalemia
    • cough
    • hypotension
    • renal impairment
  79. How do you monitor ACE Inhibitors?
    • BUN/SCr
    • electrolytes
  80. What is the MOA of ARBs?
    Antagonizes the angiotensin II AT1 receptor
  81. What are some Adverse Effects of ARBs?
    • angioedema
    • hyperkalemia
    • hypotension
    • renal impairment
  82. How do you monitor ARBs?
    • BUN/SCr
    • electrolytes
  83. What is the MOA of non-dihydropyridine CCBs?
    Inhibits Ca2+ ion influx into vascular smooth muscle and myocardium; decreases SVR, dilates coronary artery, prolongs AV node refractory period.
  84. What are some Adverse Effects of non-dihydropyridine CCBs?
    • bradycardia
    • AV block
    • arrhythmia
    • hypotension
    • heart failure
    • edema
    • constipation
  85. How do you monitor non-dihydropyridine CCBs?
    • BUN/SCr
    • LFTs
    • HR
  86. What is the MOA of dihydropyridine CCBs?
    Inhibits Ca2+ ion influx into vascular smooth muscle and myocardium.
  87. What are some Adverse Effects of dihydropyridine CCBs?
    • angina
    • edema
    • fatigue
    • dizziness
  88. How do you monitor dihydropyridine CCBs?
    Nothing listed on Drug Chart.
  89. What is the MOA of "Centrally Acting"?
    Stimulates alpha-2 adrenoreceptors.
  90. What are some Adverse Effects of "Centrally Acting"?
    • orthostasis
    • bradycardia
    • sedation
    • constipation
    • rebound hypertension
  91. How do you monitor "Centrally Acting"?
    • BUN/SCr
    • HR
  92. What is the MOA of Direct Vasodilators?
    Directly dilates peripheral vessels.
  93. What are some Adverse Effects of Direct Vasodilators?
    • headache
    • GI
    • tachycardia
  94. How do you monitor Direct Vasodilators?
    • BUN/SCr
    • CBC
    • ANA
  95. What is the MOA of Direct Renin Inhibitors?
    Decreases plasma renin activity; inhibits conversion of angiotensinogen to angiotensin I.
  96. What are some Adverse Effects of Direct Renin Inhibitors?
    • angioedema
    • hypotension
    • hyperkalemia
    • GERD
    • renal impairment
  97. How do you monitor Direct Renin Inhibitors?
    • BUN/SCr
    • electrolytes

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