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Thyroid Hormones
Levothyroxine (Synthroid)
- Replacement treatment in hypothyroidism, pituitary TSH suppression in the treatment of euthyroid goiters.
- Stimulates SNS, Increases metabolic rate of the body, increases O2 consumption, increases respirations, increases heart rate.
- Nervousness, tremor, headache, palpitations, tachycardia, hair loss.
- Apical pulse before med administration.
- Check dose carefully-mcg or mg?
- 4-6 weeks to adjust med
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Antithyroid Agents-Thidamodes
Propyltheouracil (PTU)
- Inhibits the synthesis of thyroid hormones, partially blocks conversion of T4 to T3. Increases SNS.
- Epigastric distress
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Antihypocalcemic Agents
Calcitrol (Rocaltrol)
- Management of hypocalcemia in pts. on chronic renal dialysis or with hypoparathyroidism.
- Vit. D compound that regulates ansorption of CA an Phosphate from small intestine, mineral resorption in bone, and reabsorption of phosphate from renal tubules, increase serum CA levels.
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Bisphosphonates
Alendronate (Fosamax), Risedronate (Actonel)
Acts on serum levels of CA, not directly on Parathyroid gland (PTH). Slows normal/abnormal bone resorption
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Calcitonins, Canichypercalcemic
Calcitonin, Salmon (Calcimar)
Inhibits bone resorption. Homrmones secreted by thyroid glands to balance the effects of PTH.
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Antithyroid Agents-Iodine
Strong Iodine Solution, Potassium Iodine (Thyro-Block)
Inhibits the synthesis of thyroid hormones and inhibits the release of these hormones with circulation.
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Parathyroid Hormones
Teriparatide/Forteo
Treatment of osteoporosis in Postmenopausal women at high risk for fractures. Releases calcium and phosphates metabolism in bone and kidney by binding to specific cell receptors
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