Calcium Channel Blockers
(CCB--Very Nice Drugs--verapamil, norvasc, diltiazem)
- Decrease afterload and O2 demand by dilating arterioles and decreasing myocardial contractility. (some in this classification may decrease pulse).
- HTN, Brady/Tachycardia, palpitations, peripheral edema, flush, constipation.
- Monitor P and BP. Assess frequency of angina attacks. Use orally for angina. Extended release should not be chewed, opened, or broken. Encourage high fiber diet to prevent constipation. Risk of heart block and Dig toxicity with verapamil.
- Stable or unstable angina.
- Treatment of Prinzmetal's Angina.
- Inhibits the movement of CA+ ions across the membranes of myocardial and arterial muscle cells altering the action potential and blocking muscle cell contraction.