Cardio Drugs - Dyslipidemia

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Author:
coletrain3
ID:
98237
Filename:
Cardio Drugs - Dyslipidemia
Updated:
2011-08-24 15:54:21
Tags:
Cardio drugs cardiovascular dyslipidemia medications
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Description:
Cardio Drugs used for Dyslipidemia
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  1. HMG-CoA Reductase Inhibitors
    • Rosuvastatin (Crestor)
    • Atorvastatin (Lipitor)
    • Pitavistatin (Livalo)
    • Simvastatin (Zocor)
    • Pravastatin (Pravachol)
    • Lovastatin (Mevacor, Altoprev)
    • Fluvastatin (Lescol, Lescol XL)
  2. Cholesterol Absorption Inhibitor
    Ezetimibe (Zetia)
  3. The Bomb
    Niacin
  4. Fibric Acid Derivatives
    • Gemfibrozil (Lopid)
    • Fenofibrate (Fenoglide, Lipofen, Lofibra Tabs, Tricor, Triglide)
    • Fenofibrate - micronized (Antara, Lofibra Caps)
    • Fenofibric Acid (Trilipix)
  5. Bile Acid Sequestrant
    • Colestipol (Colestid)
    • Colesevelam (Welchol)
  6. Bumblebee Tuna
    Omega-3 Fatty Acids (Lovaza)
  7. Rosuvastatin (Crestor)
    • Dosing Range: 5-40 mg
    • Frequency: 1
  8. Atorvastatin (Lipitor)
    • Dosing Range: 10-80 mg
    • Frequency: 1
  9. Pitavistatin (Livalo)
    • Dosing Range: 1-4 mg
    • Frequency: 1
  10. Simvastatin (Zocor)
    • Dosing: 5-80 mg
    • Frequency: 1
  11. Pravastatin (Pravachol)
    • Dosing Range: 10-80 mg
    • Frequency: 1
  12. Lovastatin (Mevacor)
    • Dosing Range: 10-80 mg
    • Frequency: 1-2
  13. Lovastatin (Altoprev)
    • Dosing Range: 10-60 mg
    • Frequency: 1
  14. Fluvastatin (Lescol)
    • Dosing Range: 20-80 mg
    • Frequency: 1-2
  15. Fluvastatin (Lescol XL)
    • Dosing Range: 80 mg
    • Frequency: 1
  16. Ezetimibe (Zetia)
    • Dosing Range: 10 mg
    • Frequency: 1
  17. Niacin (Niaspan)
    • Dosing Range: 500-2,000 mg
    • Frequency: 1
  18. Gemfibrozil (Lopid)
    • Dosing Range: 1200 mg
    • Frequency: 2
  19. Fenofibrate (Fenoglide)
    • Dosing Range: 40-120 mg
    • Frequency: 1
  20. Fenofibrate (Lipofen)
    • Dosing Range: 50-150 mg
    • Frequency: 1
  21. Fenofibrate (Lofibra Tabs)
    • Dosing Range: 54-160 mg
    • Frequency: 1
  22. Fenofibrate (Tricor)
    • Dosing Range: 48-145 mg
    • Frequency: 1
  23. Fenofibrate (Triglide)
    • Dosing Range: 50-160 mg
    • Frequency: 1
  24. Fenofibrate-micronized (Antara)
    Dosing Range: 43-130 mg
  25. Fenofibrate-micronized (Lofibra Caps)
    • Dosing Range: 67-200 mg
    • Therapy: 1
  26. Fenofibric Acid (Trilipix)
    • Dosing Range: 45-135 mg
    • Frequency: 1
  27. Colestipol (Colestid)
    • Dosing Range: 2-16 mg
    • Frequency: 1-2
  28. Colesevelam (Welchol)
    • Dosing Range: 2500-4375 mg
    • Frequency: 1
  29. Omega-3 Fatty Acids (Lovaza)
    • Dosing Range: 4 grams
    • Frequency: 1-2
  30. What is the MOA for Statins (HMG-CoA Reductase Inhibitors)?
    Inhibits the rate-limiting step of de novo synthesis of cholesterol.
  31. What are some adverse effects of statins/HMG-CoA Reductase Inhibitors?
    • myalgia
    • LFT elevation
    • CK elevation
    • hepatic failure
    • rhabdomyolysis
  32. How do you monitor statins?
    LFTs, S/Sx (signs & symptoms) of myalgia
  33. What is the MOA of Cholesterol Absorption Inhibitors?
    Inhibits cholesterol absorption at the brush border in the small intestine.
  34. What are some adverse effects of Cholesterol Absorption Inhibitors?
    • hepatitis
    • cholecystitis
    • cholelithasis
    • abdominal pain
    • diarrhea
  35. How do you monitor Cholesterol Absorption Inhibitors?
    Nothing listed on drug chart
  36. What is the MOA of Niacin?
    • Enhances lipoprotein lipase activity
    • Inhibits lipolysis in adipose tissue
    • Decreases VLDL production
  37. What are some adverse effects of Niacin?
    • flushing
    • abdominal pain
    • LFT elevation
    • N/V
    • hepatic failure
    • hyperglycemia
    • hyperuricemia
  38. How do you monitor Niacin?
    • LFTs
    • glucose
    • uric acid
  39. What is the MOA of Fibric Acid Derivatives?
    • Inhibits lipolysis in adipose tissue
    • Decreases production and increases clearance of apoB
    • Enhances lipoprotein lipase activity
  40. What are some adverse effects of Fibric Acid Derivatives?
    • dyspepsia
    • abdominal pain
    • N/V
    • diarrhea
    • elevated LFTs
    • cholelithiasis
    • myopathy
    • thrombocytopenia
    • anemiaa
  41. How do you monitor Fibric Acid Derivatives?
    • SCr
    • LFTs
    • CBC
  42. What is the MOA of Bile Acid Sequestrants?
    Binds intestinal bile acids preventing enterohepatic recirculation.
  43. What are some adverse effects of Bile Acid Sequestrants?
    • esophageal obstruction
    • bowel obstruction
    • fecal impaction
    • dysphagia
    • constipation
    • dyspepsia
  44. How do you monitor Bile Acid Sequestrants?
    Nothing listed on Drug Chart
  45. What is the MOA of Omega-3 Fatty Acids?
    Decreases hepatic triglyceride synthesis.
  46. What are some adverse effects of Omega-3 Fatty Acids?
    • anaphylaxis
    • dyspepsia
    • eructation
    • elevated LFTs
  47. How do you monitor Omega-3 Fatty Acids?
    LFTs

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