Pharmacology B

Card Set Information

Author:
Anonymous
ID:
98325
Filename:
Pharmacology B
Updated:
2011-08-25 00:04:34
Tags:
pharmacology
Folders:

Description:
RESPIRATORY AND CARDIOVASCULAR
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user Anonymous on FreezingBlue Flashcards. What would you like to do?


  1. Chronotropic effect
    affectting Heart Rate
  2. Inotropic effect
    effecting Contractility
  3. Dromatropic effect
    affecting Cardiac Impulse Conduction Velocity
  4. Factors affecting cardiac output
    • Preload
    • Afterload
    • Contractility
    • Heart rate
    • Cardiac Output= The amount of blood pumped by the L ventricle each minute.
    • CO= SV x HR
    • - meaning SV and HR are inversley related.
  5. Preload vs Afterload
    Ventricular filling pressure vs Systemic vascular resistance
  6. Blood Pressure Values
    a) Normal
    b) Pre-hypertensive
    c) Hypertension (stage 1)
    d) Hypertension (stage 2)
    • a) < 120/ <80
    • b) 120-139/ 80-90
    • c) 140/159/ 90-99
    • d) > 160/ >100

    systolic/diastolic
  7. 3 Systems that help regulate blood pressure
    • Sympathetic nervous system
    • - inc HR directly via Beta-receptor stimulation
    • The kidneys
    • - controls blood volume via water reabsorbtion
    • (volume is proportional to Bp)
    • Systemic/peripheral vascular resistance
    • -vasoconstriction via alpha-receptor stimulation
    • =inc resistance= HR
  8. Anti-hypertensive agents
    • Diuretics
    • Sympatholytics
    • Angiotensin Inhibitors
    • Vasodilators
  9. Diuretics (anti-hypertensive)
    • Thiazide diuretics
    • Loop Diuretics: most potent
    • K+ sparing diuretics: prevent hypokalemia, used with thiazides

    Cause and increase in renal Na+ excretion (natriuresis)= increased water excretion. This decreases blood volume and thus, decreases CO (and SVR)
  10. Thiazide Diuretics (1)
    Diuril (Chlorothiazide)

    Moderate natriuretic effect. Can cause hypokalemia
  11. Adrenergic blockers (anti-hypertensive)
    alpha 1 antagonists: cause vasodilation, reduce SVR. Can result in reflex CV stimulation or kidney reabsorbtion (renin-angioT-aldos system)

    Beta antagonists/blockers: block receptors on the heart and juxtaglomerular cells= dec HR and blood volume.

What would you like to do?

Home > Flashcards > Print Preview