Neuro Phys test 2

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Anonymous
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98806
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Neuro Phys test 2
Updated:
2011-08-28 21:38:10
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UWS
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test 2
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  1. Positive emotion vs negative
    pos - vta increase nAc and decrease Amy

    neg - raphe increase amy and decrease nAc
  2. TOM- theory of mind
    ability to infer what others are thinking
  3. NA
    • from locus ceruleus - Lc
    • attention control
    • learning and memory
    • control of emotion
    • deep non-rem sleep
  4. His
    • from mamillotuberal nuc- MTn
    • attention control and arousal
    • modulation of body energy stores
    • supports learning and memory
  5. 5HT
    • Raphe nuclei - nR
    • inhibition of behavior
    • modulation of emotion
    • support of learning and memory
    • control of non rem sleep
  6. Ach
    • pontopeduncular tegmental nuc. and nuc. basalis
    • PPT and NB

    • memory and learning
    • modulation of emotion
    • REM sleep
  7. DA
    • ventral tegmental area and nuc. accumbens
    • VTA and nAc
    • "reward" network
    • control of emotion
    • memory and learning
  8. 5 neurochemical signaling systs
    • single source divergent
    • use SP, PP, RP connections
  9. Cingulate cortex
    • attention control
    • tectum -> pulvinar -> cingulate gyrus, PFc

    controlled by the PF working memory
  10. Working memory
    • directs all activity
    • 5 single source divergent networks -> medial dorsal thal. nuc -> PFc
  11. Working memory tasks
    • Planning - what is useful info
    • selection and suppresion - focus on relevant info
    • task monitoring - keeping relevant info first
    • coding and trigger. consolidation- short term -> LTM
  12. Right LPF cortex
    perceptual processes
  13. Left LPF cortex
    language/semantic info
  14. working memory deficits
    dementia
  15. medial PFC and orbital PFC
    emotion
  16. NT's in NREM sleep
    • NA
    • 5HT
  17. NT's in REM sleep
    ACh
  18. trigger for sleep
    adenosine
  19. sensation perception
    • awake:
    • bottom-up and top-down

    • rem:
    • top-down only
  20. movement in sleep
    • NREM - transitory and involuntary
    • REM- triggered but inhibited
  21. 5 modulatory networks
    • each a unique transmitter
    • single -source divergent
    • the first networks wired developmentally
    • all work together
  22. Glial cell fxns
    • regulate avail. glucaose and O2
    • guide neurite outgrowth - development
    • control reuptake of NT's
    • control diffusion of NT's
    • buffer increaess in extracell K+
    • control density and distribution of ion channels
    • makes saltatory impulse possible
    • forms BBB
  23. Microglia 3 personalities
    • resting
    • activated
    • phagocytic
  24. tripartite synapse
    • presynaptic neuron
    • postsyn neuron
    • glial cell
  25. Brain mapping methods/tests
    EEG - oldest, good time, poor location

    PET - measures glu and blood flow, good location, poor time, radioactive

    fMRI - newest shows O2 areas, best
  26. Interneurons
    • inhibitory
    • produce rapid alterations in TIME WINDOWS of synaptic convergence, allows binding, crucial for learning and memories
  27. GABAergic
    inhibitory
  28. interneurons:
    • lack dendritic spines
    • connections with principal cells
    • inhibitory networks- gap junctions and electrical coupling
    • all GABA NT but different NP's
  29. Neurons
    • Principal - spiny
    • interneurons - non spiny
  30. principal spiny cells
    • glutamatergic - excitatory
    • 80% of neurons
    • synapses are absent
  31. Feed-forward
    • elicited excitation - sustain the excitatory discharge
    • elicited inhibition- produces on-off gating response
  32. feed-back
    • recurrent excitation- accelerates original cell output
    • recurrent inhibition- slowly supress cell output
  33. autapses
    conections with self
  34. glutamergic
    excitatory
  35. 2 circuit types
    • hierarchical
    • local
  36. hierarchical circuit
    • uses SP, PP, RP
    • from area to area
  37. local circuts
    • feed-forward and feed-back
    • excitatory and inhibitory
  38. Hebbian Assembly - distributed system
    • hubs of activity
    • each node near or far from one another
    • communicates via SP, PP, RP

    are hierarchiacally organized, local division within

    Sculpted, glued together by synaptic plasticity
  39. Neural darwinism
    • edelman
    • environment/experience selects channels/builds brain networks
  40. Synaptic plasticity
    • HEBB
    • neural assemblies are put together with plastic learning
    • those tracts used more grow, not used die
  41. weeks until break
    • 3 so stop being lazy
    • work your ass off

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