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kornberg
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Pharmacodynamics
The study of the drug concentration and drug effects on the body
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Pharmaceutic Phase
phase in which the drug becomes solution so that it can cross the biologic membrane
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Excipients
fillers and inert substances used in drug preparation
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Disintergration
break down of a tablet into smaller particles
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Dissolution
dissolving of the smaller particles in the GI fluid before absorption
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Rate limiting
time it takes a drug to disintegrate and dissolve to become available for absorption
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Pharmacokinetics
process of drug movement to acheive drug action
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Passive absorption
mainly diffusion; doesn't require energy
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Active absorption
requires a carrier like an enzyme or protein to move a substance against a concentration gradient
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Pinocytosis
process by which cells carry a substance across their membrane by engulfing the substance
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First pass effect
also called hepatic first pass; process by which a substance passes to the liver first; the liver metabolizes the substance
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