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At risk of bacterial infections as well as fungal infections & opportunistic molds (Aspergillus)
Deficiency in cell-mediated immunity
At risk of infection by organisms with an intracellular phase (viruses; Mycobacteria; Listeria; Cryptococcus; & toxoplasma) as well as Pneumocystis
Deficiency in humoral immunity
At risk of extracellular organisms - particularly encapsulated bacteria (S. pneumoniae; H. influenzae; N. meningitidis)
Conditions causing neutropenia
Cytotoxic & other drugs; acute leukemia; congenital defects (chronic granulomatous disease; etc)
Conditions causing deficiency in cell-mediated immunity
HIV; glucocorticoids; immunosuppression (as with solid organ transplantation); lymphomas (Hodgkin's especially)
Conditions causing deficiency in humoral immunity
Splenectomy; multiple myeloma; common variable immunodeficiency (CVID); X-linked agammaglobulinemia
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